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Chronic liver disease: Four coffees a day

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The researchers found that drinking three to four cups of coffee a day can help reduce the risk of chronic liver disease. Researchers from the University of Southampton and the University of Edinburgh found drinking caffeinated and decaffeinated coffee was associated with a reduced risk of developing liver conditions, including liver disease, when the data from research compared to not drinking coffee.

Dr Kennedy and his team analyzed data from UK Biobank on 495,585 participants with known coffee consumption. The participants were followed for around 10 years to monitor who developed liver conditions. Overall, 78% drank ground or instant caffeinated or decaffeinated coffee, while 22% did not drink any type of coffee. During the period, there were 3,600 cases of chronic liver disease, including 301 deaths. The researchers warned that as coffee consumption was only reported when participants first enrolled in the study, the study does not account for any changes in the amount or type of coffee they consumed over the study period, and the statistical data seems to be quite biased if considered for the mass people around the world. The participants were predominantly white and from high social-economic backgrounds.

The benefit peaked at three to four cups a day, the research suggests. Scientists found that coffee drinking had a 21% reduction in risk of chronic liver disease, a 20% reduced risk of chronic or fatty liver disease and a 49% reduced risk of death from liver disease. The benefits were seen in people who drank ground coffee. Instant coffee also showed a reduced risk of liver disease, but it was smaller than the reduction seen in ground coffee drinkers. “Coffee is widely accessible and the benefits we see from our study may mean it could offer a potential preventative treatment for chronic liver disease. This would be especially valuable in countries with lower income and worse access to healthcare and where the burden of chronic liver disease is highest,” said Dr Oliver Kennedy, the lead author.

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